Heavy Cannabis Use Linked to Schizophrenia, Especially among Young Men

The French psychiatrist Jacques-Joseph Moreau published a book called Hashish and Mental Illness in 1845, the same year that Scientific American brought out its first issue. In it, he explored his own experiences  with the drug cannabis at the Paris-based Club des Hachichins—some of which took place alongside the likes of Victor Hugo, Honoré de Balzac and Charles Baudelaire. Two years earlier Moreau described the “undescribable delights” of a “marvelous substance.” But in his 1845 book, he noted in great clinical detail the similarities to psychosis when ingesting high doses.

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